BAY 80-6946

CAS No. 1032568-63-0

BAY 80-6946 ( Copanlisib )

Catalog No. M10156 CAS No. 1032568-63-0

BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BAY 80-6946
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.
  • Description
    BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.
  • Synonyms
    Copanlisib
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1032568-63-0
  • Formula Weight
    480.52
  • Molecular Formula
    C23H28N8O4
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:0.002 mg/mL (0.0 mM); Ethanol:0.01 mg/mL (0.02 mM); Water:0.002 mg/mL (0.0 mM)
  • SMILES
    COC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patnaik A, et al. J Clin Oncol, 29, 2011, (suppl, abstr 3035)
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