BAY 80-6946

CAS No. 1032568-63-0

BAY 80-6946 ( Copanlisib )

Catalog No. M10156 CAS No. 1032568-63-0

BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 In Stock
10MG 65 In Stock
25MG 115 In Stock
50MG 200 In Stock
100MG 335 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BAY 80-6946
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.
  • Description
    BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 2.
  • Synonyms
    Copanlisib
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1032568-63-0
  • Formula Weight
    480.52
  • Molecular Formula
    C23H28N8O4
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:0.002 mg/mL (0.0 mM); Ethanol:0.01 mg/mL (0.02 mM); Water:0.002 mg/mL (0.0 mM)
  • SMILES
    COC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patnaik A, et al. J Clin Oncol, 29, 2011, (suppl, abstr 3035)
molnova catalog
related products
  • Vps34-IN-1

    Vps34-IN-1 is a potent, selective inhibitor of class III PI3K Vps34 with IC50 of 25 nM.

  • PI3K inhibitor X

    PI3K inhibitor X (XL-147 analog) is a derivative of XL147 that acts as a reversible inhibitor.

  • GSK1059615

    GSK1059615 is a highly potent, dual PI3K/mTOR inhibitor.